Karl ZIEGELBAUER: search on Z-Library

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1

Product-related research: how research can contribute to successful life-cycle management

Peter Sandner, Karl Ziegelbauer

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 874 KB

english, 2008

2

Computer-aided target selection—prioritizing targets for antifungal drug discovery

Frank Spaltmann, Martin Blunck, Karl Ziegelbauer

Journal:

Drug Discovery Today

Year:

1999

Language:

english

File:

PDF, 206 KB

english, 1999

3

Doxorubicin-induced activation of NF-κB in melanoma cells is abrogated by inhibition of IKKβ, but not by a novel IKKα inhibitor

Nadin Pletz, Margarete Schön, Karl Ziegelbauer, Steffen Emmert, Ningshu Liu, Matthias Dobbelstein, Michael P. Schön

Journal:

Experimental Dermatology

Year:

2012

Language:

english

File:

PDF, 404 KB

english, 2012

4

Strategic alliance management: lessons learned from the Bayer-Millennium collaboration

Karl Ziegelbauer, Ronald Farquhar

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 135 KB

english, 2004

5

Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: Improvement of in vitro activity

Toshiki Murata, Mitsuyuki Shimada, Hiroshi Kadono, Sachiko Sakakibara, Takashi Yoshino, Tsutomu Masuda, Makoto Shimazaki, Takuya Shintani, Kinji Fuchikami, Kevin B Bacon, Karl B Ziegelbauer, Timothy B

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 266 KB

english, 2004

6

Genomics: success or failure to deliver drug targets?

Ulrich AK Betz, Ronald Farquhar, Karl Ziegelbauer

Journal:

Current Opinion in Chemical Biology

Year:

2005

Language:

english

File:

PDF, 103 KB

english, 2005

7

Monoclonal antibody therapeutics: Leading companies to maximise sales and market share

Ziegelbauer, Karl, Light, David R

Journal:

Journal of Commercial Biotechnology

Year:

2008

Language:

english

File:

PDF, 84 KB

english, 2008

8

Surface antigen change during differentiation of Trypanosoma brucei

ZIEGELBAUER, KARL, OVERATH, PETER

Journal:

Biochemical Society Transactions

Year:

1990

Language:

english

File:

PDF, 332 KB

english, 1990

9

Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p

Ekkehard Leberer, Karl Ziegelbauer, Axel Schmidt, Doreen Harcus, Daniel Dignard, Josée Ash, Lyne Johnson, David Y. Thomas

Journal:

Current Biology

Year:

1997

Language:

english

File:

PDF, 1.40 MB

english, 1997

10

The novel PI3 kinase inhibitor, BAY 80-6946, impairs melanoma growth in vivo and in vitro

Schneider, Philine, Schön, Margarete, Pletz, Nadin, Seitz, Cornelia S., Liu, Ningshu, Ziegelbauer, Karl, Zachmann, Karolin, Emmert, Steffen, Schön, Michael P.

Journal:

Experimental Dermatology

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

11

High Throughput Assay to Detect Compounds That Enhance the Proton Permeability of Candida albicans Membranes

ZIEGELBAUER, Karl, GRUSDAT, Gerda, SCHADE, Andreas, PAFFHAUSEN, Wolfgang

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1999

File:

PDF, 1.79 MB

1999

12

High-Throughput Assay for Inorganic Pyrophosphatases Using the Cytosolic Enzymes of Saccharomyces cerevisiae and Human as an Example

Jens Rumsfeld, Karl Ziegelbauer, Frank Spaltmann

Journal:

Protein Expression and Purification

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

13

In situ analysis of FGFR2 mRNA and comparison with FGFR2 gene copy number by dual-color in situ hybridization in a large cohort of gastric cancer patients

Kuboki, Yasutoshi, Schatz, Christoph A., Koechert, Karl, Schubert, Sabine, Feng, Janine, Wittemer-Rump, Sabine, Ziegelbauer, Karl, Krahn, Thomas, Nagatsuma, Akiko Kawano, Ochiai, Atsushi

Journal:

Year:

2017

Language:

english

File:

PDF, 2.55 MB

english, 2017

14

Development of a high-throughput fluoroimmunoassay for Syk kinase and Syk kinase inhibitors

Noriyuki Yamamoto, Haruki Hasegawa, Hitomi Seki, Karl Ziegelbauer, Takahiro Yasuda

Journal:

Analytical Biochemistry

Year:

2003

Language:

english

File:

PDF, 218 KB

english, 2003

15

Allosteric MEK1/2 Inhibitor Refametinib (BAY 86-9766) in Combination with Sorafenib Exhibits Antitumor Activity in Preclinical Murine and Rat Models of Hepatocellular Carcinoma

Schmieder, Roberta, Puehler, Florian, Neuhaus, Roland, Kissel, Maria, Adjei, Alex A, Miner, Jeffrey N, Mumberg, Dominik, Ziegelbauer, Karl, Scholz, Arne

Journal:

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

16

Radium-223 inhibits osseous prostate cancer growth by dual targeting of cancer cells and bone microenvironment in mouse models

Suominen, Mari I, Fagerlund, Katja M, Rissanen, Jukka P, Konkol, Yvonne M, Morko, Jukka P, Peng, ZhiQi, Alhoniemi, Esa J, Laine, Salla K, Corey, Eva, Mumberg, Dominik, Ziegelbauer, Karl, Käkönen, Sann

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 14.86 MB

english, 2017

17

Promoting drug discovery by collaborative innovation: a novel risk- and reward-sharing partnership between the German Cancer Research Center and Bayer HealthCare

Ruth Wellenreuther, Dietrich Keppler, Dominik Mumberg, Karl Ziegelbauer, Monika Lessl

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

18

Signal Transduction through Homologs of the Ste20p and Ste7p Protein Kinases can Trigger Hyphal Formation in the Pathogenic Fungus Candida albicans

Ekkehard Leberer, Doreen Harcus, Ian D. Broadbent, Karen L. Clark, Daniel Dignard, Karl Ziegelbauer, Axel Schmidt, Neil A. R. Gow, Alistair J. P. Brown and David Y. Thomas

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 2.09 MB

english, 1996

19

A dual labelling method for measuring uptake of low molecular weight compounds into the pathogenic yeast Candida albicans

Ziegelbauer, Karl

Journal:

Medical Mycology

Year:

1998

Language:

english

File:

PDF, 517 KB

english, 1998

20

A selective novel low-molecular-weight inhibitor of IκB kinase-β (IKK-β) prevents pulmonary inflammation and shows broad anti-inflammatory activity

Karl Ziegelbauer, Florian Gantner, Nicholas W Lukacs, Aaron Berlin, Kinji Fuchikami, Toshiro Niki, Katsuya Sakai, Hisayo Inbe, Keisuke Takeshita, Mina Ishimori, Hiroshi Komura, Toshiki Murata, Timothy

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 334 KB

english, 2005

21

Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis

Meier, Julia C., Haendler, Bernard, Seidel, Henrik, Groth, Philip, Adams, Robert, Ziegelbauer, Karl, Kreft, Bertolt, Beckmann, Georg, Sommer, Anette, Kopitz, Charlotte

Journal:

Cancer Medicine

Year:

2015

Language:

english

File:

PDF, 4.32 MB

english, 2015

22

Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro

Karl ZIEGELBAUER, Margret QUINTEN, Heinz SCHWARZ, Terry W. PEARSON, Peter OVERATH

Journal:

Year:

1990

Language:

english

File:

PDF, 540 KB

english, 1990

23

Genomic organization of an invariant surface glycoprotein gene family of Trypanosoma brucei

Karl Ziegelbauer, Gloria Rudenko, Rudo Kieft, Peter Overath

Journal:

Molecular and Biochemical Parasitology

Year:

1995

Language:

english

File:

PDF, 1008 KB

english, 1995

24

Proteolytic release of cell surface proteins during differentiation of Trypanosoma brucei

Ziegelbauer, Karl, Stahl, Bernd, Karas, Michael, Stierhof, York Dieter, Overath, Peter

Journal:

Year:

1993

Language:

english

File:

PDF, 2.31 MB

english, 1993

25

Sorafenib/MEK inhibitor combination inhibits tumor growth and the Wnt/β‑catenin pathway in xenograft models of hepatocellular carcinoma

Huynh, Hung, Ong, Richard, Goh, Kah Yong, Lee, Liek Yeow, Puehler, Florian, Scholz, Arne, Politz, Oliver, Mumberg, Dominik, Ziegelbauer, Karl

Journal:

International Journal of Oncology

Year:

2019

Language:

english

File:

PDF, 1.36 MB

english, 2019

26

Leveraging Human Genetics to Estimate Clinical Risk Reductions Achievable by Inhibiting Factor XI

Georgi, Benjamin, Mielke, Johanna, Chaffin, Mark, Khera, Amit V., Gelis, Lian, Mundl, Hardi, van Giezen, J. J. J., Ellinor, Patrick, Kathiresan, Sekar, Ziegelbauer, Karl, Freitag, Daniel F.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.02 MB

english, 2019

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